Glucosamine/Chondroitin with MSM and SAM-e combines the most popular components found in joint support products. Scientific studies indicate that Glucosamine Enhances provide the building blocks for supporting cartilage. Chondroitin Enhances to maintain joint cartilage. MSM is an organic source of sulfur and synergistically promotes the benefits of Glucosamine and Chondroitin to support cartilage health. This supplement also contains SAM-e (S-adeno-sylmethionine),a diverse ingredient not readily available in everyday diet.