Nattokinase is an enzyme derived from "natto", a traditional fermented soy food popular in Japan. During the natto production process B. subtilis natto, a friendly bacteria, ferments boiled, non-GMO soybeans, releasing nattokinase. Best Nattokinase contains pure nattokinase enzyme with all Vitamin K removed.

Nattokinase is an enzyme derived from "natto", a traditional fermented soy food popular in Japan. During the natto production process B. subtilis natto, a friendly bacteria, ferments boiled, non-GMO soybeans, releasing nattokinase. Best Nattokinase contains pure nattokinase enzyme with all Vitamin K removed.

Suitable for vegetarians.

Best Glucosamine Sulfate contains pure glucosamine sulfate, as confirmed by HPLC testing. Glucosamine sulfate consists of glucosamine, an amino sugar extracted from shellfish skeletons. "Chitin", the resilient polysaccharide that forms the structural framework of animal shells, is a long-chain polymer consisting of many glucosamine molecules linked together. The purified glucosamine is then sulfated and stabilized with potassium chloride. Note: Best Glucosamine Sulfate is sodium-free. It contains 24-26% potassium chloride.

Serrapeptase is a proteolytic enzyme isolated from the non-pathogenic bacteria Serratia species found in the digestive tract of the Japanese silkworm. The enzyme is used by the worms to digest their cocoons. Serrapeptase has been used as a nutritional supplement in Europe and Asia for nearly three decades. Each vegetarian capsule of Best Serrapeptase contains enteric-coated, acid stable granules of pure serrapeptase designed for optimal absorption in the intestinal tract.

Acetyl-L-Carnitine (ALC) is a naturally occurring form of L-Carnitine, a vitamin-like nutrient synthesized in the body from the amino acids lysine and methionine. ALC serves as a transport molecule for "active acetate," which is a source of fuel for metabolic processes that take place in cells. ALC carries active acetate (the "Acetyl" portion) directly into the mitochondrion, the cell's energy-generating structure. Active acetate is used to produce cellular energy in the form of ATP. Both L-Carnitine and ALC serve as fat carriers. Unlike L-Carnitine, ALC readily crosses the blood-brain barrier, where it has specific benefits for brain neurons. When taken orally, ALC has been shown to increase ALC levels in both blood and cerebrospinal fluid, demonstrating its uptake in the brain. Best Acetyl-L-Carnitine consists of Biosint Acetyl-L-Carnitine, which is manufactured in Italy by the Sigma Tau company. It is derived from a base of pharmaceutical-grade L-Carnitine manufactured using an FDA-approved process that fully complies with international monograph standards for carnitine production. Known as a global leader in L-Carnitine research, Sigma Tau holds numerous patents for production of L-Carnitine, and its L-Carnitine derivatives, such as ALC, which are used in clinical trials.

5-HTP (5-hydroxytryptophan) is a naturally-occurring metabolite of the essential amino acid tryptophan. 5-HTP for use in dietary supplements is derived from the seeds of the Griffonia simplicifolia plant.

Standardized Saw palmetto berry extract, guaranteed to contain 90 percent fatty acids and sterols.

5-HTP (5-hydroxytryptophan) is a naturally-occurring metabolite of the essential amino acid tryptophan. 5-HTP for use in dietary supplements is derived from the seeds of the Griffonia simplicifolia plant.

Best French Red Wine Extract contains BioVin Advanced, a French Red Wine extract made from whole red wine grapes. BioVin Advanced contains 5% red wine trans-resveratrol and 30-35% red wine polyphenols, including anthocyanins and other flavonoids. Each capsule of Best French Red Wine Extract provides the resveratrol equivalent of 3 glasses of red wine or 12 glasses of white wine.

The whole grape constituents in BioVin Advanced enhance the body's antioxidant defenses to counteract the effects of free radicals. * Resveratrol is involved in activating the human enzyme SIRT1, which is involved in regulating metabolism and healthy weight control.* Resveratrol and red wine polyphenols have been shown to support healthy cardiovascular function and promote healthy aging.

Made from Premium French Red Wine

BioVin Advanced is a red wine extract manufactured in France from premium red grapes abundant in polyphenols and resveratrol. The grapes are fermented into wine, which then undergoes filtration to remove any impurities. The final product is purely extracted and washed with grain alcohol before the alcohol is evaporated, resulting in a potent concentrate. Animal studies of French red wine polyphenols have demonstrated effects in supporting cardiovascular health and scavenging free radicals. Studies of resveratrol also suggest support of cardiovascular function and promotion of longevity and healthy aging in animals. Best French Red Wine Extract containing BioVin Advanced retains the natural color of premium red wine grapes.

Benfotiamine (S-benzyolthiamine-O-monophosphate) is a synthetic derivative of thiamin, belonging to the family of compounds known as "allithiamines." Benfotiamine is fat-soluble and thus more bioavailable and physiologically active than thiamin. Characteristic of the allithiamines is an open thiazole ring within the chemical structure of these thiamine-related compounds, making them fat (lipid) soluble. In contrast, thiamine, which is water soluble, has a closed thiazole ring. The lipid solubility of benfotiamine, conferred by this open ring, increases its bioavailablity. Benfotiamine is readily absorbed at higher doses, in contrast to absorption of water-soluble thiamin salts, which decreases at higher doses, due to saturation of absorption sites in the intestines. In a double-blind, cross-over trial, comparing bioavailability of benfotiamine to that of thiamine in 12 subjects, benfotiamine caused an average 5-fold greater increase in blood thiamine levels than thiamin mononitrate, with a concomitant greater thiamine concentration in erythrocytes (red blood cells). Benfotiamine readily passes through intestinal mucosal cells, where it is converted into physiologically active thiamine. Benfotiamine inceases blood levels of thiamine pyrophosphate (TPP), the primary thiamin co-enzyme.

Best Curcumin C3 Complex with Bioperine contains a standardized extract of Curcuma longa root, commonly known as "Turmeric". Turmeric is a yellow spice used in curried dishes. In the Far East, turmeric is valued for more than just its culinary applications. The herb has been employed in the Ayurvedic healing tradition for centuries , and is a common household remedy in India. The active ingredients in Curcuma longa are a group of plant substances called curcuminoids. Known collectively as “curcumin,” curcuminoids have demonstrated potent antioxidant properties in scientific studies. Curcuminoids benefit joints and other tissues by Enhanceing to neutralize free-radicals. Curcuminoids are responsible for turmeric’s distinctive yellow color.

Curcuma C3 Complex supplies 95% total curcuminoids, including curcumin, bisdemethoxy curcumin and demethoxy curcumin. Bioperine is an extract of Black Pepper fruit that contains 95-98% piperine. Bioperine is added as a natural bioenhancer to promote absorption of the product.

Native to Southeast Asia, Curcuma longa is a tall tropical shrub with large oblong leaves and pale yellow flowers. The genus “Curcuma” belongs to the Zingiberaceae family, which includes ginger. The plant possesses a large root structure with fleshy, bulbous underground parts called “rhizomes.” These rhizomes, known as turmeric root, are harvested at maturity, dried and cured for commercial use. Chemical analysis shows that dried turmeric contains essential and volatile oils, with a curcuminoid content of 2.5 to 5.0 %. In addition to its popularity as a spice, turmeric is used as a dye for cloth and coloring agent in foods and cosmetics, thanks to its rich yellow color. Turmeric also serves as a preservative, probably owing to the antioxidant and antimicrobial properties of curcumin. Extracts of Curcuma longa have demonstrated in vitro effects against harmful organisms and anti-fungal effects. Turmeric is named in ancient Ayurvedic and Chinese herbal texts as a traditional folk remedy. Historically, turmeric was used externally for wounds, and sprains, and internally for digestive complaints, rheumatism, liver Malfunction of mind or bodys, coughs and colds.

Suitable for vegetarians

Alpha-lipoic acid (ALA, thioctic acid) is a naturally occurring vitamin-like nutrient that has been intensely investigated as a therapeutic agent for a variety of conditions involving the body’s nervous, cardiovascular, immune, and detoxification systems. It exists as two enantiomers or stereoisomers: R-(+)-lipoic acid (RLA) and S-(-)-lipoic acid (SLA). It is produced in small amounts in the liver and other body tissues, where it is needed by enzymes to catalyze numerous essential chemical reactions in the body. For instance, ALA is essential inside the mitochondria of cells, where it is needed to metabolize glucose and direct calories into energy production.

ALA is considered to be a multimodal supplement because, aside from its enzymatic role in energy production, it acts by multiple mechanisms and displays diverse pharmacologic and antioxidant properties. Recently discovered is ALA’s ability to switch the regulation of several genes linked to cell survival, soreness and oxidative stress. So in addition to its enzymatic role, ALA is a powerful antioxidant and performs a number of other vital functions related to its ability to modify the expression of various genes. ALA is therefore not so much a direct benefit to cells, but rather an indirect aid that "kick starts" declining function in cells, Enhanceing them recover the functions that came more easily and naturally in the young.

Researchers at Oregon State University’s Linus Pauling Institute for Micronutrient research have found that our body’s natural lipoic acid levels decline markedly with age, but can be replenished through dietary supplementation. They describe ALA as an "age-essential" micronutrient and have shown that, when fed to rats, it markedly improves mitochondrial function and ameliorates many signs of aging (Hagen et al. 2002; Suh et al. 2004; University 2007). ALA is also being extensively studied in humans by researchers across the globe, and so far has been found to exhibit a number of both confirmed and potential benefits for health and longevity.