Sulfur is one of the essential minerals, ranked as a macronutrient in the vertebrate diet. Earlier methionine work and ongoing MSM research indicates that it is the structure of the sulfur donor molecule, not the amount of sulfur, that is critical.

MSM is a form of sulfur found in the tissues and fluids and is the major form of sulfur in the human body. It is an important nutrient for joint tissue where it functions in the stabilization of the connective tissue matrix of cartilage, tendons, and ligaments. It is also important in the health and function of the hair, nails, skin, connective tissue, enzymes, hormones and immunoglobulins. Without adequate and properly delivered sulfur, life functions would cease.

MSM deficiencies have been shown to be associated with inflammatory problems, gastrointestinal dysfunction, slow wound healing, brittle toenails and fingernails, Defense mechanism of body problems, brittle hair, skin problem and rashes.