Inositol hexaphosphate (IP-6), also known as phytate, is a naturally occurring component of plant fiber that may possess antioxidant, anticancer, and other beneficial properties. Natural IP-6 exists primarily as a poorly absorbed form because it is mixed with protein and minerals like calcium, magnesium, or potassium to form a salt. So, in its natural state as a fiber component, IP-6 is poorly absorbed. Studies have shown that pure IP-6 is significantly more bioavailable.

Cardiovascular disease. Kidney stones. Immune-suppressing conditions like AIDS. Viral, fungal, and protozoal infections.

Cancer

Virtually all research suggesting healthful effects from taking IP-6 involve animals and not people. It is not known whether IP-6 would be useful for humans and if so, what the optimal amount should be. Usual dietary intakes range from 1–1.5 grams phytate per day.

IP-6 is associated with dietary fiber and thus is naturally present in a wide variety of plant foods, especially wheat bran, whole grains, and legumes.

Talk to your doctor about any side effect that seems unusual or which is especially bothersome.

Acute overdose: Not known. Although phytate in foods has been associated with reduced mineral absorption, this effect may be important at very high intakes. Chronic overdose: None. What to do: For an acute overdose, call your doctor, emergency medical services (EMS), or the nearest poison control center immediately. For symptoms of chronic overdose, contact your doctor.

Virtually all research suggesting healthful effects from taking IP-6 involve animals and not people. Persons should be aware of this aspect of the drug.