| Product Description |
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Plant sterols are proven to help reduce cholesterol - scientific evidence proves that including plant sterols in your diet helps to lower blood total and LDL cholesterol levels. Following a diet low in saturated fat and cholesterol, and consuming 400mg or more of plant sterols twice a day may reduce the risk of heart disease.
This powerful blend of plant sterols is backed by research to maintain healthy cholesterol levels already within normal limits.
It combines clinically-studied ingredients: This unique combination
of pantethine and phytosterols works together to:
- Support heart health and healthy cholesterol production
- Limit absorption of cholesterol from food
- Limit re-absorption of cholesterol from bile
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| Suggested Use
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| One (1) tablet three (3) times daily, with or immediately before each meal.
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| Ingredients/Supplement Facts
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| Supplement Facts |
Serving Size: 1 Tablet |
| Ingredients |
Amount |
%DV |
| Total Carbohydrate |
<1g |
<1% |
| Sodium |
10mg |
<1% |
Proprietary Phytosterol Blend
beta sitosterol, campesterol, stigmasterol, brassicasterol, and other plant sterols |
400mg |
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| Pantethine |
200mg |
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| Other
Ingredients:cellulose, modified cellulose gum, silicon dioxide, magnesium stearate, modified cellulose, soy lecithin, and carnauba wax. |
sugar, yeast, wheat, gluten, dairy products, artificial coloring, artificial flavoring, preservatives or ingredients of animal origin. This product contains natural ingredients; color variations are normal.
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| Additional Information |
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How Does It Work?:
Cholesterol is both produced by the body and obtained from food.
Endogenous cholesterol is formed by human cells, particularly liver
cells. The liver produces varying amounts, usually about 1,000 milligrams a day.
Exogenous cholesterol is absorbed through the gastrointestinal tract from
food. Approximately 400 to 500
mg (or more) can be contained in foods from animal sources (especially
egg yolks, meat, poultry, fish, seafood and whole-milk dairy products).
Phytosterols
Simply stated, phytosterols are the “fat” of plants. The proprietary phytosterol
blend found in Cholesterol Shield occurs naturally and is structurally
similar to cholesterol, though its activity is very different.† The major
phytosterols found in nature are β-sitosterol, campesterol, and stigmasterol.
The typical daily diet contains 100-300 mg phytosterols.
At usual levels of consumption, phytosterols have little
effect on blood cholesterol concentration. However, because phytosterols share
structural similarities with cholesterol, they bind to sites in the intestines
that would be used for cholesterol binding were they not blocked. Dietary
consumption of phytosterols in the 1200 mg per dose range reduces intestinal and
biliary cholesterol absorption and helps to retain healthy cholesterol levels
that are already within normal limits.
Phytosterols appear to decrease the solubility of cholesterol
in the intestines, thus interfering with its absorption. Phytosterols also
increase bile salt excretion in the intestines. In humans, administration of
phytosterols significantly decreased cholesterol absorption from food by 38%.
Pantethine
Cholesterol Shield also contains pantethine, a
precursor of coenzyme A (CoA). CoA is involved in 70 enzymatic pathways,
including cholesterol synthesis.8 Pantethine modulates the action of several
enzymes, including 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase.
Pantethine inhibits the activity of HMG-CoA reductase; this
enzyme plays an important part in the pathway of cholesterol synthesis.
Human studies have demonstrated that pantethine is beneficial
for retaining healthy cholesterol levels that are already within normal limits.†13-17
Additionally, studies have shown that 600 mg of pantethine per day is required
to achieve this beneficial support.† No studies have found beneficial effects at
lower dosages.
A year-long trial with pantethine was conducted in 24
individuals. The treatment was well tolerated with no subjective complaints or
detectable side effects. Blood lipid assays repeated after 1, 3, 6, 9, and 12
months of treatment revealed consistent benefit for retaining healthy
cholesterol levels that are already within normal limits.
In another study, the effect of pantethine (various mg doses
daily for 3 to 6 months) was evaluated in 72 individuals. The results
demonstrated that pantethine was tolerated well and retained healthy cholesterol
levels that were already within normal limits.
Combination of Phytosterols and Pantethine
Since pantethine and phytosterols exert their beneficial effects in different
ways, it is theorized that a product combining both complimentary ingredients
may synergistically provide even greater levels of significant support.
Mechanisms of Action on Cholesterol Metabolism
Ingredients
Mechanisms
Phytosterols
Helps reduce cholesterol absorption from food†
Helps increase bile salt excretion†
Pantethine
Helps inhibit cholesterol biosynthesis†
Helps inhibits fatty acid biosynthesis†
Helps increase fatty acid oxidation (catabolism)†
Why should healthy cholesterol levels that are already within normal limits
be retained?
Cholesterol is a soft, waxy substance found among the lipids (fats) in the
bloodstream and in all cells. Cholesterol is essential for the formation of cell
membranes. It is also plays a role in the synthesis of certain hormones, the
formation of cholic acid in the liver (relating to the formation of bile salts),
and is utilized by the skin in the support of skin integrity. However, a high
level of cholesterol in the blood is a major risk factor for coronary heart
disease, which can lead to a heart attack.
High serum cholesterol levels are associated with coronary
artery disease. Specifically, cholesterol deposits in the arteries develop into
plaques that reduce or block blood flow. In addition, dense connective tissue
deposits lead to arteries that become stiff and unyielding (sclerosis).
Eventually, hard calcifications form. This is known as “hardening of the
arteries.” Arteries that have lost flexibility are easily ruptured, and in the
areas where plaques protrude into flowing blood, blood clots may develop. Heart
attacks or stroke may then result.
Estimates are that 100.9 million American adults have total
blood cholesterol values of 200 mg/dL and higher, and about 40.6 million
American adults have levels of 240 or above. In adults, total cholesterol levels
of 240 mg/dL or higher are considered high risk, and levels from 200 to 239 mg/dL
are considered borderline-high risk.19 The National Cholesterol
Education Program has developed the following guidelines for serum cholesterol
levels.
NCEP's ATP-III guideline
Serum cholesterol
Desirable
Borderline
High/High risk
Total (mg/dL)
< 200
200-239
=>240
LDL (mg/dL)
<130
130-159
=>160
HDL (mg/dL)
> 40
< 35
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Warning! Read carefully before using Cholesterol Shield |
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Scientific evidence proves that including plant sterols in your diet helps to lower blood total and LDL cholesterol levels. Following a diet low in saturated fat and cholesterol, and consuming 400 mg or more of plant sterols twice a day may reduce the risk of heart disease.
If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.
ETI is an FDA-registered Drug Establishment and an AFSI-certified producer of particular organic product(s).
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