HOW DOES IT WORK?
Cell Forté with IP-6 and Inositol provides nutritional support
of immune function including healthy cell development and natural killer cell
activity.
Healthy Cell Development
Healthy cells are characterized by structural and organizational integrity. They
have a cytoskeleton composed of bundles of proteins that provide the structure
and shape of the cell. Distinct structure and function is an important component
in healthy cell development. Healthy cells differentiate from other cells, with
disparate and distinct potential for cell development.1-3
Healthy cells have cell membranes with complex coverings that determine what
molecules can enter and leave the cell. Healthy cell surface function is vital
to healthy cell development. A number of biochemical substances are present on
cell surfaces and allow healthy cell interaction with other healthy cells.
Healthy cells develop from intact and functioning genetic material.1-3
Natural Killer Cells
Natural killer (NK) cells are a subset of peripheral blood lymphocytes. In
contrast to other lymphocytes, NK cells do not require communication with other
immune cells prior to activity. NK cells mediate a variety of important healthy
immune system functions, including overall surveillance and healthy
immunoregulation. Increases in healthy NK cell activity provide support of
healthy immune function.4,5
Inositol Hexaphosphate
Inositol hexaphosphate (IP-6 or phytic acid) is an inositol molecule with six
phosphate groups attached. Inositol hexaphosphate is ubiquitous (found
everywhere) in the plant kingdom and abundant in cereals and legumes.6,7
In smaller amounts, IP-6 is contained in most mammalian cells, where it supports
cellular functions.8-14 In addition, IP-6 functions as an
antioxidant.15,16
Inositol
Inositol is a water soluble, ubiquitous 6-carbon sugar. Recognized as part of
the vitamin B complex group, inositol is an important dietary and cellular
constituent. Major food sources include beans, citrus fruit, nuts, rice, veal,
pork, and wheat germ.17 Inositol supports healthy nerve transmission,
healthy fat metabolism, and is needed for cell membrane structure and integrity.18-23
Inositol Hexaphosphate and Inositol
While independently these molecules support immune health, the unique
combination of IP-6 and inositol functions synergistically. Research indicates
the combination of IP-6 and inositol supports stronger healthy cell development
and increased natural killer cell activity as opposed to either compound alone.24-26
Through phosphorylation, inositol molecules can accept up to six phosphate
groups. Lower inositol phosphates (IP-1, IP-2, IP-3, and IP-4) act as cellular
messengers with varying degrees of activity.27 IP-3, a highly active
molecule, has numerous cellular supportive and cellular communication functions.28
Inositol hexaphosphate is hypothesized to support healthy cellular function
through dephosphorylation into IP-3. When inositol is combined with IP-6, it can
accept the phosphates that are liberated from the breakdown of IP-6, thereby
increasing the intracellular levels of beneficial IP-3 molecules.24-26
Research suggests that IP-6, and its lower phosphorylated, forms help support
healthy cell development.26-28
Both the molecular ratio and the weight ratio of IP-6 to inositol are
important in Cell Forté with IP-6 and Inositol:
| |
Molecular Ratio |
Weight |
| IP-6 |
1 |
400 mg |
| Inositol |
1 |
110 mg |
One molecule of IP-6 is four times the weight of an inositol molecule. A 1:1
molecular ratio, the ratio that yields maximum IP-3 production, is obtained by
combining 400 mg IP-6 to 110 mg of inositol. Any variance from this 1:1
molecular ratio results in a significant reduction of IP-3 molecules produced.1
It is the molecular ratio, unique to the patent that distinguishes Cell Forté
with IP-6 and Inositol from other products. Therefore, no other product can
yield the optimal amount of IP-3 that Cell Forté with IP-6 and
Inositol can deliver.
REFERENCES
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Abulkalam M. Shamsuddin; patent date: January 21, 1992.
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- Shamsuddin AM, Vucenik I. Mammary tumor inhibition by IP6: a review.
Anticancer Res. 1999;19:3671-3674.
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keratinocyte growth. J Cell Physiol. 1988;135:416-424.
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- Sun XY, Edvinsson L, Yoo H, Wahlestedt C, Hedner T. Effects of some novel
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- Payrastre B, Missy K, Giuriato S, Bodin S, Plantavid M, Gratacap M.
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- Shamsuddin AM, Ullah A, Chakravarthy AK. Inositol and inositol
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- Vucenik I, Yang GY, Shamsuddin AM. Inositol hexaphosphate and inositol
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- Shamsuddin AM. IP6: An anticancer cocktail: IP-6 and inositol. In: IP6:
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