How Does It Work?:
Esberitox is a unique blend of wild indigo root, coneflower root, and white cedar leaf that has been widely used in Europe for decades. This powerful combination of herbs fortifies the Defense mechanism of body, Enhanceing to strengthen the body's natural defense mechanisms.†¹

Research has shown that the Esberitox combination provides a broader range of activity than any individual component alone.† This additive effect is produced via the actions and interactions of the concentrated botanical extracts. Although the activity of the individual components overlap in some way, each herb is unique in how it enhances immune function.†¹

The following table summarizes the key benefits of each ingredient:¹

Clinical Research Findings
The safe and efficacious use of Esberitox in both children and adults has been documented in over thirty clinical and scientific studies. Unlike Echinacea, which has generated both negative and positive results, studies on the Esberitox combination have yielded only positive findings.

Defense mechanism of body Support
Several studies have examined the ability of Esberitox to quickly and effectively enhance Defense mechanism of body function.†^2-8 The powerful combination promotes the body's resistive functions by stimulating the production and activity of critical immune cells.†

One randomized, double-blind, placebo controlled, multi-center study involving 263 adults, found that improvement was noticeable after only two days of supplementation - three days earlier than the placebo group.†² Similar benefits have been noted in children, where safety and tolerability have been established for those as young as two years of age.†³

Esberitox is especially beneficial when extra Defense mechanism of body support is desired.† Clinical research has demonstrated that supplementation increased the rate of phagocytosis by 7.4%, whereas the rate in the placebo group decreased 3.2%.†^1,4 Phagocytosis is a process through which immune cells rid the body of waste and foreign bodies. Esberitox has also been shown to double the level of killer cell activity and the lymphocyte count in individuals in need of immune support.* These findings provide strong evidence of Esberitox's ability to stimulate the Defense mechanism of body.†⁵

Safety
Numerous studies have been done with various dosages and preparations of echinacea. Research indicates that echinacea preparations are generally considered very safe, and few adverse effects have been reported in the literature.†

However, because of the documented immune-stimulating action of echinacea, there is potential for a theoretical interaction in individuals for whom immune system enhancement is contraindicated. Therefore, we have included the following cautionary statement on the label as a conservative measure for our consumers: “Not recommended for individuals with autoimmune problems, HIV Problem created due to harmful organism, progressive systemic problem, or who are allergic to echinacea or other flowers of the same Compositae (or Asteraceae) family”.

The potential for interaction was examined at the 1999 American Herbal Products Association International Echinacea Symposium. The conclusion drawn following an extensive review of the literature was that these precautionary warnings are based more on theoretical arguments than on specific scientific data.⁹

Conclusion
Esberitox has a long history of safe and effective use. This unique combination of herbs possesses a broader spectrum of activity than Echinacea alone, and when taken initially, can dramatically enhance the function of the Defense mechanism of body.†

References:
1. Wüstenberg P, Henneicke-von Zepelin HH, Köhler G, Stammwitz U. Efficacy and Mode of Action of an Immunomodulator Herbal Preparation Containing Echinacea, Wild Indigo, and White Cedar. Advances in Therapy. 1999;16(1):51-70.
2. Henneicke-von Zepelin HH, Hentschel C, Schnitker J, Kohnen R, Kohler G, Wustenberg P. Efficacy and safety of a fixed combination phytoa substance used in managing discomfort in the Favorable Effects of the common cold (acute viral respiratory tract Problem created due to harmful organism): results of a randomised, double blind, placebo controlled, multicentre study. Curr Med Res Opin. 1999;15:214-227.
3. Kohler G, Elosge M, Hasenfuss I, Wustenberg P. Children's dosage of phytopharmaceuticals: representative, exemplary, age-stratified dosage practice for the herbal combination of active substances in Esberitox. Zeitschrift fur Phytotherappie. 1998;19:318-322.
4. Qadripur SA. Influencing the phagocytic ability of granulocytes with drugs. Ther d Gegenw. 1976;115:1072-8.
5. Kindzel'skii LP, Zlochevskaia LL, Tsyganok TV, Shabaeva MM. The effect of natural immunomodulators on the lymphocytic natural killer activity in patients with malignant lymphoproliferative problems. Lik Sprava. 1995;(1-2):146-8.
6. Freitag U, Stammwitz U. Shortened duration of pertussis Problem created due to harmful organism through non-specific immuno-stimulation. Kinderarzt. 1984;8:1068-1071.
7. Hauke W, Kohler G, Henneicke-von Zepelin HH, Freudenstein J. Esberitox N as supportive therapy when providing standard antibiotic Favorable Effects in subjects with a severe bacterial Problem created due to harmful organism (acute exacerbation of chronic bronchitis). Chemotherapy. 2002;48:259-266.
8. Stolze H, Forth H. Antiobiotic Favorable Effects can be optimized by adjuvant immunostimulation. Der Kassenarzt. 1983;23:43-48.
9. Panel Discussion: Possible contraindications an side effects of echinacea. Presented at: The 1999 AHPA International Echinacea Symposium. Kansas City, MO. June 3-5, 1999.