Yet an individual's level of Alpha-Lipoic acid is actually very low and there is evidence that this level declines further with age. To overcome this issue, supplementation of Alpha-Lipoic acid is reasonable under any conditions that lead to a decline of the body's antioxidant status, like sports, stress, intake of unbalanced nutrition and during illnesses. The daily dose is about 300 milligrams. According to a number of Human studies, this dose is effective as well as safe, provided that a supplement of good quality is used.

Due to its unique chemical structure, Alpha-Lipoic acid is capable of attaching to s0-called free radicals or reactive oxygen species (ROS). Free radicals are highly reactive molecules from numerous origins such as pollution, radiation, alcohol, cigarette smoke or certain drugs. Free radicals can interfere with cell membranes, enzymes or DNA, may cause severe damage to tissues and increase the effects of cell aging and problems. Like other antioxidants, Alpha-Lipoic acid interacts with free radicals and converts them to entities, which can no longer harm cell structures.

As part of this antioxidant network, Alpha-Lipoic acid may Enhance alleviate the effects of oxidative stress for the human body. Oxidative stress plays a major role in the development of diabetes and nerve problems. Thus Alpha-Lipoic acid is also presumed to be effective in reducing complications associated with type II diabetes as well as protecting nerve cells from damage. Diabetic cells are characterized by high blood glucose contents. The consumption of glucose is carried out by certain enzyme complexes, which employ Alpha-Lipoic acid as an essential cofactor. Alpha-Lipoic acid stimulates the uptake of blood glucose into muscle tissue, increases glycolysis and augments glucose utilization. Furthermore, Alpha-Lipoic acid inhibits gluconeogenesis. There has also been evidence that it also has a positive influence on insulin action by stimulating insulin sensitivity. As high blood pressure, weight problems or Deposition of substances on the wall of blood vessel, leading to narrowing of blood vessel often accompanies diabetic complications, Alpha-Lipoic acid supplementation may Enhance to alleviate symptoms associated with these conditions.

In general, Alpha-Lipoic acid improves the overall cellular function of the human body. As many problems share an inability of proper cellular function due to cell damage, Alpha-Lipoic acid might also be beneficial in various complications such as neurological Malfunction of mind or bodys, heart problem or immune malfunction.

Given its unique features, it is not surprising that this universal antioxidant has found widespread use as a dietary supplement, particularly in anti-aging appliances. Especially for the U.S. market, Significant growth for Alpha-Lipoic acid is expected over the next few years. Contributing to this growth are intensive efforts in the R&D departments of the mose well recognized nutraceutical companies all over the world. Recent research interests include the improvement of the stability, bioavailability and duration of its efficacy by developing sustained release formulations.